Trans-Urethral Resection of Bladder Tumor (TURBT)

Q 1. What is TURBT?

A. Transurethral resection of bladder tumour (TURBT) is the surgical removal (resection) of bladder tumours. This procedure is both diagnostic and therapeutic. It is diagnostic because the surgeon removes the tumour and all additional tissue necessary for examination under a microscope (histological assessment).

TURBT is also therapeutic because complete removal of all visible tumours is the treatment for this cancer.
Complete and correct TURBT is essential for good prognosis. In some cases, a second surgery is required after several weeks.

Q 2. What is the procedure involved in TURBT?

A. A cystoscopy is often used to detect the presence of bladder cancer. If there is cancer, a TURBT is performed to remove the tumour and to determine whether it has spread to the muscle layer of the bladder wall. This operation involves the telescopic removal of the malignant tissue with heat diathermy and temporary insertion of a catheter for bladder irrigation.

Trans-Urethral Resection of Bladder Tumor (TURBT)

 

Q3. What should I expect before the procedure?

A. If you are a smoker, we advise you to stop smoking straight away.
If you are taking blood thinning medication on a regular basis, you must discuss this with your urologist because these drugs can cause increased bleeding after surgery. There may be a balance of risk where stopping them will reduce the chances of bleeding but this can result in increased clotting, which may also carry a risk to your health. This will, therefore, need careful discussion with regard to risks and benefits. Aspirin does not usually need to be stopped but will be the decision of your surgeon.

You will usually be admitted on the same day as your surgery, or a day before. You will normally undergo pre assessment on the day of your clinic. After admission, you will be seen by members of the medical team which may include the consultant, junior urology doctors and nurse.

You will be asked not to eat or drink for six hours before surgery and, immediately before the operation, you may be given a pre-medication by the anaesthetist which will make you dry-mouthed and pleasantly sleepy.

Please be sure to inform your urologist in advance of your surgery if you have any of the following:

  • Co-morbidities like Diabetes, Hypertension, Coronary artery disease or, stroke, epilepsy
  • Any transmissible disease like HIV/AIDS, Hepatitis B or C etc
  • Presence of implants, pacemakers, graft etc
  • You are taking prescription drugs like-
    • Blood thinners/ anti-platelets i.e. Warfarin, ecosprin, clopidogrel etc
    • Anti-epileptics like phenytoin, valproate etc

Q4. What happens during the procedure?

A. Either a full general anaesthetic (where you will be asleep throughout the procedure) or a spinal anaesthetic (where you are awake but unable to feel anything from the waist down) will be used. All methods minimise pain; your anaesthetist will explain the pros and cons of each type of anaesthetic to you.

A telescope is passed into the bladder and a thorough visual inspection (Cystoscopy) is performed. This is followed by removal of the malignant tissue using heat diathermy. The tumor chips are evacuated using suction and sent for pathological analysis. A catheter is usually inserted after the procedure. The catheter may be used to administer local chemotherapy into your bladder immediately after the procedure. It is left in your bladder for an hour then drained afterwards.

The procedure takes 45 to 60 minutes.
You will usually be given injectable antibiotics before the procedure, after checking for any allergies.

Q 5. What are the side effects and complications?

A. Most procedures have a potential for side effects. You should be reassured that, although all these complications are well recognised, the majority of patients do not suffer any problems after a urological procedure.

Common (greater than one in 10)

  • Mild burning or bleeding on passing urine for short period after operation
  • Temporary insertion of a catheter for bladder irrigation
  • Need for additional treatments to bladder in attempt to prevent recurrence of tumours including drugs instilled into the bladder

Occasional (between one in 10 and one in 50)

  • Infection of bladder requiring antibiotics
  • No guarantee of cancer cure by this operation alone
  • Recurrence of bladder tumour and/or incomplete removal

Rare (less than one in 50)

  • Delayed bleeding requiring removal of clots or further surgery
  • Damage to drainage tubes from kidney (ureters) requiring additional therapy
  • Injury to the urethra causing delayed scar formation
  • Perforation of the bladder requiring a temporary urinary catheter or open surgical repair

Q 6. What can I do to prevent complications and side effects?

A. There are several measures that can help you prevent complications such as:

  • Drink plenty of fluids. Drink at least two litres of water or juice daily for two to three days. This will dilute your urine, reduce discomfort when urinating, and prevent blood clotting.
  • Take your medication as per your doctor’s advice.
  • Stay active. As soon as you feel you are able, resume your daily activities to help speed up recovery. You may find that you need more sleep than usual during the first few days after your hospital discharge.
  • Do not lift anything heavier than 2 kg 2 weeks after surgery.
  • Refrain from sexual activity for up to 2 weeks.
  • Avoid straining during bowel movement. Use a stool softener such as an osmotic laxative if necessary.
  • Do not cycle or exercise intensively.
  • Avoid household chores such as window cleaning, vacuuming, or gardening.
  • Do not use alcohol for 24-48 hours.
  • Watch out for infection. If you develop a fever (over 37.8°C) or if your urine becomes cloudy and thick, you could have an infection. Contact your doctor so that he/ she can decide whether you need antibiotics. If you find it painful to urinate the blood clots or to urinate at all, contact your doctor immediately.
  • Smoking: We strongly advise anyone with bladder cancer to stop smoking.

Q 7. How long will I be on catheter?

A. The catheter is generally removed after two to three days, following which urine can be passed in the normal way. In case there has been deep resection then catheter will be kept for seven to ten days.
At first, it may be painful to pass your urine and it may come more frequently than normal. Any initial discomfort can be relieved by tablets or injections and the frequency usually improves within a few days.

Q 8. How long will I stay in the hospital?

A. The average hospital stay is usually 36 to 48 hours.

Q 9. What should I expect when I get home?

A. When you leave hospital, you will be given a discharge summary of your admission. This holds important information about your inpatient stay and your operation.

Most patients feel tired and below par for a week or two because this is major surgery. Over this period, any frequency usually settles gradually.

Q 10. What else should I look out for?

A. If you experience increasing frequency, burning or difficulty on passing urine or worrying bleeding, contact your urologist.

In the event of severe bleeding, passage of clots or sudden difficulty in passing urine, you should contact your urologist immediately since it may be necessary for you to be re-admitted to hospital.

Q 11. What else should I know about?

A. Your biopsy report will be available in 10 to 14 days. Depending on the biopsy results, further investigations (eg x-ray, CT scan), instillation of drugs into your bladder (chemotherapy or immunotherapy) or a further admission may be arranged for you.

Q 12. What is the duration of recovery period?

A. The symptoms of an overactive bladder may take three months to resolve whereas the flow is improved immediately. Sexual activity can be resumed as soon as you are comfortable, usually after three to four weeks.
Most patients require a recovery period of two to three weeks at home before they feel ready for work. We recommend three to four weeks rest before resuming any job, especially if it is physically strenuous and you should avoid any heavy lifting during this time.

Q 13. Will I need a second endoscopic surgery (Re-TURBT)?

A. Residual tumour tissue is sometimes observed after removal of stage Ta and T1 tumours. Moreover, there is a risk that staging of these tumours after removal is too low (under-staging) because the most aggressive part of the tumour has not been examined or has been missed during removal.

To achieve complete tumour removal and assess the correct stage of the tumour, re-TURBT is recommended 4–6 weeks after the primary TURBT in some cases:

  • After incomplete initial TURBT
  • No muscle is present in the tissue taken in the initial TURBT (unless tumours are low-grade stage Ta tumours or primary CIS)
  • For all stage T1 tumours
  • For all high-grade tumours (except primary CIS)