A. The failure of the testicles (or “testes”) to descend into the scrotum (the skin sac below the penis) is called “cryptorchidism”. It is also called having hidden or undescended testicles. The condition is generally uncommon but often affects boys born prematurely.
A. As a male foetus grows, the testicles appear in the abdomen near the kidneys. During the seventh month of development, the testicles start to descend to the groin. They should reach their final position in the scrotum by 6 months after birth.
The testicles make sperm and testosterone, the male sex hormone. An undescended testicle may produce hormones, but the ability to make sperm is disrupted.
At 1 year of age, nearly 1% of all full-term male infants have cryptorchidism. This is the most common birth defect of the sex organs in new-born male infants.
Usually, only one testicle is affected, but both testicles are undescended in about 10% of children with cryptorchidism.
A. The main indication of an undescended testicle is not feeling it in the scrotum. The testicle is typically discovered to be missing during an infant’s examination after birth. Regular check-ups will be needed to monitor cryptorchidism for the first 6 months. If the testicle does not descend on its own, treatment will be needed.
A. Possible risk factors include:
A. Cryptorchidism is classified as “palpable” or “non-palpable”. A palpable undescended testicle can be felt on examination. A non-palpable testicle cannot be felt. Approximately 70% of all undescended testicles are palpable.
A palpable undescended testicle may have halted during a normal descent. Maybe the testicle grew in the wrong place and is outside of the scrotum (ectopic). Perhaps a muscle reflex causes the testicle to move back and forth between the scrotum and the abdomen (retractile).
A non-palpable undescended testicle is either located up inside the abdomen or even may be absent. It may be above the genital organs (inguinal ring), near a kidney, between the rectum and the bladder, or near the muscle wall that covers the stomach.
Treatment is based on the location and presence of the testicles. Ectopic palpable testicles require surgery. A retractile palpable testicle should be watched closely until puberty in case it returns to the abdomen (ascending). If both undescended testicles are non-palpable and sexual differentiation problems exist, an endocrinological and genetic evaluation should be done.
A. Physical examination: Physical examination is the only way to classify an undescended testicle as palpable or non-palpable. Imaging studies do not help. The doctor’s examination will include a visual description of the scrotum with the child lying on his back and with crossed legs.
If one testicle is undescended and non-palpable and the other is enlarged, a testicle may be missing or undeveloped. The abdomen should be examined visually to make sure the undescended testicle is not ectopic.
Diagnostic laparoscopy: Internal examination using a fibre-optic tube-like instrument with a camera (endoscope) is the only way to reliably diagnose a non-palpable testicle. The surgeon inserts the endoscope through a small cut in the abdomen (laparoscopy).
Examination under general anaesthesia before laparoscopic assessment is recommended because some originally nonpalpable testes become palpable.
A. Boys with retractile testes (testicles that may move between the scrotum and the groin) do not need medical or surgical treatment but require close follow-up until puberty.
A. If the testicle does not descend on its own, treatment will be needed. The goal of treatment is to prevent problems making sperm and hormones. Treatment should be done at around 1 year of age or 18 months at the latest.
Orchidopexy: The main treatment for cryptorchidism is surgery to move the testicle into the scrotum (orchidopexy). This surgery is nearly 100% successful. If a testicle has not fully descended by the age of 6 months, surgery should be performed within the subsequent year. Delaying treatment can increase the risk of infertility later in life.
Surgery for a non-palpable testicle includes an examination with laparoscopy. This is also done with the boy under general anaesthesia. Laparoscopy is the best way to look for an undescended testicle in the abdomen. Removal or repositioning can be done during laparoscopy if needed.
Hormonal therapy: In some cases, hormone injections may be used to try to prompt the testicle to move to the scrotum on its own. This treatment is not common and only suggested to boys with bilateral undescended testes, to preserve fertility.
A. Most men who had one undescended testicle in childhood are able to father children. The ability to reproduce of men after the orchidopexy before the age of 18 months is nearly the same to the other men. Men who had two undescended testicles have a higher risk of infertility.
Boys with an undescended testicle have an increased risk of developing testicular cancer. Screening both during and after puberty is recommended.
Boys with retractile testes do not need medical or surgical treatment but require close follow-up until puberty.